Genome India Data

On January 9, 2025, the Department of Biotechnology (DBT) issued a call for proposals for translational research using Genome India data, targeting India-based scientists. The original submission deadline of February 28, 2025, was later extended to March 31, 2025.

About the Genome India Project

• The 10,000 Human Genome Project collected blood samples and phenotype data from over 20,000 individuals across 83 population groups (30 tribal and 53 non-tribal).
• Preliminary findings based on genetic data from 9,772 individuals were published as a Commentary in Nature Genetics on April 8, 2025.

Key Issues Raised

• Despite the vast phenotypic data collected (height, weight, waist/hip circumference, blood pressure, blood counts, glucose, lipid profiles, liver and kidney function tests), neither the original proposal call nor the addendum disclosed these datasets.
• The Commentary article, which listed available phenotype data, was published after the proposal submission deadline, leaving many researchers uninformed.
• GenomeIndia’s official website also did not detail the available phenotype data.

Government Response:

• A DBT spokesperson clarified that anthropometric and blood biochemistry data were collected to ensure the health status of individuals sampled.
• The spokesperson cited the One Nation One Subscription scheme, aimed at providing free journal access; however, it currently benefits only researchers from public institutions.

Accessibility Disparity:

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• Researchers from the 20 institutions involved in Genome India were aware of the phenotype data.
• External researchers were at a disadvantage, lacking essential information needed to submit competitive proposals.

Significance:

• The controversy highlights urgent concerns about data transparency, equal research opportunity, and the need for fair access to publicly funded scientific resources in India.

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