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IRRI Scientists Discover Rice Varieties with Antioxidant and Anti-Cancer Properties

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Context:

Scientists at the Philippines-based International Rice Research Institute (IRRI) have identified a few rice varieties with anti-oxidant and anti-cancer properties.

  • Institute:
    International Rice Research Institute (IRRI), Philippines
  • Research Publication:
    Journal – Food Hydrocolloids and Health

Key Research Highlights

  • Sample Size:
    • Screened 1.32 lakh rice accessions worldwide.
    • Focused on 800 pigmented (coloured) rice varieties for detailed analysis.
  • Discovery:
    • Identified 6 pigmented rice lines with very high antioxidant levels comparable to superfoods like blueberries and chia seeds.
    • These six rice lines exhibited strong anti-cancer effects in laboratory tests on colorectal and breast cancer cell lines.
  • Unique Feature:
    • Extracts showed cytotoxicity (killing effect) only in cancer cells, sparing healthy cells, unlike many chemotherapeutic drugs which harm healthy cells too.
    • This suggests a safer treatment profile.

Testing and Supplement Development

  • In Vitro Bioavailability:
    • Tests showed antioxidant and anti-cancer biomolecules were absorbed during the gastric phase.
  • Rice Bran Extract Supplement:
    • Produced by safe ethanol extraction and microencapsulation, forming a water-soluble multi-nutrient supplement.
    • 7.5 ÎĽg/mL dose showed anti-cancer effects comparable to some chemotherapy drugs in cell line tests.
  • Retention of Properties:
    • Cooking the rice retains about 70% of antioxidant and anti-cancer benefits.

Notable Rice Varieties Identified

  • Ketan Hitam (purple rice): Origin – Indonesia
  • Balatino (purple rice): Origin – Philippines
  • Kintuman (red rice): Origin – Philippines

Significance

  • Potential development of functional foods and nutraceuticals targeting cancer prevention.
  • Promotes dietary solutions with fewer side effects compared to traditional chemotherapy.
  • Offers new opportunities for agricultural and health sectors to combat cancer through natural foods.

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    • SIDBI Previous Year Question Papers (SIDBI PYQ)

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