Context:
On January 9, 2025, the Department of Biotechnology (DBT) issued a call for proposals for translational research using Genome India data, targeting India-based scientists. The original submission deadline of February 28, 2025, was later extended to March 31, 2025.
About the Genome India Project
- The 10,000 Human Genome Project collected blood samples and phenotype data from over 20,000 individuals across 83 population groups (30 tribal and 53 non-tribal).
- Preliminary findings based on genetic data from 9,772 individuals were published as a Commentary in Nature Genetics on April 8, 2025.
Key Issues Raised
- Despite the vast phenotypic data collected (height, weight, waist/hip circumference, blood pressure, blood counts, glucose, lipid profiles, liver and kidney function tests), neither the original proposal call nor the addendum disclosed these datasets.
- The Commentary article, which listed available phenotype data, was published after the proposal submission deadline, leaving many researchers uninformed.
- GenomeIndia’s official website also did not detail the available phenotype data.
Government Response:
- A DBT spokesperson clarified that anthropometric and blood biochemistry data were collected to ensure the health status of individuals sampled.
- The spokesperson cited the One Nation One Subscription scheme, aimed at providing free journal access; however, it currently benefits only researchers from public institutions.
Accessibility Disparity:
- Researchers from the 20 institutions involved in Genome India were aware of the phenotype data.
- External researchers were at a disadvantage, lacking essential information needed to submit competitive proposals.
Significance:
- The controversy highlights urgent concerns about data transparency, equal research opportunity, and the need for fair access to publicly funded scientific resources in India.
