Eli Lilly Launches Mounjaro (Tirzepatide) in India for Diabetes and Obesity

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Source: TH

Product Launch

  • Company: Eli Lilly and Company (U.S.-based pharmaceutical major)
  • Drug: Mounjaro (tirzepatide)
  • Approval: Received marketing authorisation from the Central Drugs Standard Control Organisation (CDSCO) in India.
  • Form: Single-dose vial

Medical Benefits

  • Indications:
    • Obesity
    • Overweight
    • Type 2 diabetes
  • Mechanism: Activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors.
  • Clinical Trial Results:
    • Average weight loss over 72 weeks:
      • 21.8 kg at 15 mg dose
      • 15.4 kg at 5 mg dose

Pricing in India

  • 2.5 mg vial: โ‚น3,500
  • 5 mg vial: โ‚น4,375
  • Monthly cost (weekly doses): โ‚น14,000 to โ‚น17,500 (dose-dependent)
  • Price Comparison:
    • U.S. price: $1,000โ€“$1,200 per month (โ‚น86,000 to โ‚น1 lakh)
  • Company statement: Pricing reflects Lillyโ€™s commitment to affordable access in India.

Growing Market Landscape in India

  • GLP-1 class drug demand:
    • Market worth hundreds of billions of dollars
    • Semaglutide, a key drug in this class, to go off-patent in March 2026.
  • Key competitors preparing generics:
    • Mankind Pharma Ltd.
    • Alkem Labs Ltd.
    • Dr. Reddyโ€™s Laboratories Ltd.
  • Existing market leaders:
    • Novo Nordiskโ€™s Rybelsus (oral semaglutide) launched in 2022; holds 65% market share.
    • Other weight-loss medications: dulaglutide, liraglutide.

Market Growth

  • Anti-obesity drug market in India:
    • โ‚น137 crore in November 2020
    • Expanded to โ‚น535 crore by November 2024 (as per Pharmatrac).

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